Salicylic acid
Salicylic acid is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target acid-sensing ion channel 3.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| infections | D007239 |
| skin and connective tissue diseases | D017437 |
Trade Name
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Drug Products
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EMA
New Drug Application (NDA)
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Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| 111medco 2% salicylic acid cleansing bar | C200263 | 2023-12-12 |
| 24 alopecia reliefshampoo | unapproved drug other | 2020-08-08 |
| 28.5% salicylic acid | unapproved drug other | 2018-04-06 |
| 3 in 1 cleanser | OTC monograph final | 2020-09-16 |
| 3-1 acne treatment pads | C200263 | 2024-10-09 |
| 30 day acne treatment kit | C200263 | 2024-11-04 |
| 45% urea cream 2% salicylic acid | C200263 | 2024-11-08 |
| aavrani dry scalp rescue serum | C200263 | 2023-10-25 |
| ac out spot stop serum | unapproved drug other | 2012-09-25 |
| acence tea tree tock blemish spot | OTC monograph final | 2016-01-22 |
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Indications
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Agency Specific
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ATC Codes
D: Dermatologicals
— D01: Antifungals for dermatological use
— D01A: Antifungals for topical use
— D01AE: Other antifungals for topical use in atc
— D01AE12: Salicylic acid
— D02: Emollients and protectives
— D02A: Emollients and protectives
— D02AF: Salicylic acid emollient and protective preparations
M: Musculo-skeletal system drugs
— M02: Topical products for joint and muscular pain
— M02A: Topical products for joint and muscular pain
— M02AC: Preparations with salicylic acid derivatives, topical for joint and muscle pain
N: Nervous system drugs
— N02: Analgesics
— N02B: Other analgesics and antipyretics in atc
— N02BA: Salicylic acid and derivatives, analgesics and antipyretics
P: Antiparasitic products, insecticides and repellents
— P02: Anthelmintics
— P02D: Anticestodals
— P02DA: Salicylic acid derivative anticestodals
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01B: Antiinflammatory agents, ophthalmologic
— S01BC: Antiinflammatory agents, non-steroidal, ophthalmologic
— S01BC08: Salicylic acid
HCPCS
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Clinical
Clinical Trials
4507 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Coronary artery disease | D003324 | — | I25.1 | — | 2 | 3 | 2 | 12 | 18 |
| Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | 2 | 2 | 2 | 11 | 16 |
| Coronary disease | D003327 | — | — | — | 2 | 2 | 2 | 10 | 15 |
| Coronary restenosis | D023903 | EFO_0004224 | — | — | 2 | 3 | 2 | 5 | 11 |
| Peripheral arterial disease | D058729 | EFO_0004265 | — | — | — | 2 | 1 | 4 | 7 |
| Peripheral vascular diseases | D016491 | EFO_0003875 | I73.9 | — | — | 2 | 1 | 4 | 7 |
| Vascular diseases | D014652 | EFO_0004264 | I77 | — | — | 2 | 1 | 3 | 6 |
| Coronary occlusion | D054059 | — | I21 | — | — | — | 1 | 1 | 2 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | — | — | 1 | — | 7 | 8 |
| Dual anti-platelet therapy | D000080903 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
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Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Stroke | D020521 | EFO_0000712 | I63.9 | — | — | — | — | 4 | 4 |
| Atherosclerosis | D050197 | EFO_0003914 | I25.1 | — | — | — | — | 3 | 3 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | — | — | — | 3 | 3 |
| Arterial occlusive diseases | D001157 | EFO_0009085 | — | — | — | — | — | 2 | 2 |
| Intermittent claudication | D007383 | EFO_0003876 | I73.9 | — | — | — | — | 2 | 2 |
| Heart diseases | D006331 | EFO_0003777 | I51.9 | — | — | — | — | 2 | 2 |
| Ischemia | D007511 | EFO_0000556 | — | — | — | — | — | 1 | 1 |
| Chronic limb-threatening ischemia | D000089802 | — | — | — | — | — | — | 1 | 1 |
| Thromboembolism | D013923 | — | — | — | — | — | — | 1 | 1 |
| Coronary artery bypass | D001026 | EFO_0003776 | — | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Salicylic acid |
| INN | — |
| Description | Salicylic acid is a monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. It is obtained from the bark of the white willow and wintergreen leaves. It has a role as an antiinfective agent, an antifungal agent, a keratolytic drug, an EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor, a plant metabolite, an algal metabolite and a plant hormone. It is a conjugate acid of a salicylate. |
| Classification | Small molecule |
| Drug class | anti-inflammatory agents (salicylic acid derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | O=C(O)c1ccccc1O |
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Salicylic acid
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Salicylic acid
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Sulfur
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Trends
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Safety
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35,434 adverse events reported
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